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A smaller body needs less energy

doi:10.1007/s00125-016-4186-y 39

Afamelanotide (Scenesse): first approved MSH analog Afamelanotide, formerly NDP-alpha-MSH (Nle 4 -D-Phe 7 -alpha-MSH), is a linear 13-amino acid analog of alpha-MSH bearing the same two key substitutions as MT-II (Nle 4 , D-Phe 7 )

Cardiovascular Benefits: Promotes angiogenesis and new blood vessel growth Reduces cardiac fibrosis after injury Increases heart cell survival in ischemic conditions Decreases inflammatory cytokine expression Supports lymphangiogenesis and vascular remodeling Its anti-fibrotic properties make it especially beneficial in heart failure and post-infarct remodeling

D., Rao, M., Gilbertson, D